Hippocampal volume and cognitive performance in long-standing Type 1 diabetic patients without macrovascular complications

© 2006 The Authors. Journal compilation © 2006 Diabetes UK. Diabetic Medicine , 23 , 1268–1274 the metabolic syndrome were entered as categorical variables (instead of the metabolic syndrome as a single entity), only hypertension and dyslipidaemia ( P < 0.001 for both), along with older age, male sex and smoking history, showed independent associations with incident CVD events (data not shown). In conclusion, these results indicate that the presence of metabolic syndrome is associated with a moderately increased risk of incident CVD events in Type 2 diabetic individuals, independent of a broad spectrum of potential confounders. Thus, the new IDF definition of the syndrome can perform well as a marker for classifying Type 2 diabetic individuals according to their risk for future CVD. Further prospective studies are needed to validate the prognostic value of the new IDF definition in different populations.